People

Faculty

Manor Haim, Professor Emeritus

Phone:  (972)-4-8293456

Selected Publications

 

 

Selected Telomerase publications of the Manor laboratory:

1. Sima Benjamin, Nava Baran, and Haim Manor (2000). Interference footprinting analysis of telomerase elongation complexes. Molecular and Cellular Biology 20:4224-4237.

2. Nava Baran, Yonit Haviv, Beena Paul and Haim Manor (2002) Studies on the minimal lengths required for DNA primers to be extended by the Tetrahymena telomerase: Implications for primer positioning by the enzyme. Nucleic Acids Research 30: 5570-5578.

3. Shlomit Cohen, Eyal Jacob and Haim Manor (2004) Effects of single-stranded DNA binding proteins on primer extension by telomerase. Biochim.Biophys.Acta 1679, 129-140. 

4. Erez Romi, Nava Baran, Marina Gantman, Michael Shmoish, Bosun Min,     Kathleen Collins and Haim Manor (2007) High-resolution physical and     functional mapping of the template adjacent DNA binding site in catalytically active telomerase. Proceedings of the National Academy of Sciences of the USA 104: 8791-8796.
 

5. Karin Kertesz Rosenfeld, Tamar Ziv, Svetlana Goldin, Fabian Glaser and Haim Manor (2011) Mapping of DNA Binding Sites in the Tetrahymena Telomerase Holoenzyme Proteins by UV Cross-Linking and Mass Spectrometry. Journal of Molecular Biology, 410, 77-92    

6. Svetlana Goldin, Karin Kertesz Rosenfeld, and Haim Manor (2011) Mapping of DNA  binding sites in the RNA subunit of the Tetrahymena telomerase holoenzyme, in preparation.

 

Selected Translin publications of the Manor laboratory:

 

1. Anat Aharoni, Nava Baran and Haim Manor (1993). Characterization of a multisubunit human protein which selectively binds single stranded d(GA)n and d(GT)n sequence repeats in DNA. Nucleic Acids Res. 21, 5221-5228.

 

2. Eyal Jacob, Lev Pucshansky, Eleanor Zeruya, Nava Baran and Haim Manor (2004) The human protein Translin specifically binds single-stranded microsatellite repeats, d(GT)n, and G-strand telomeric repeats, d(TTAGGG)n: A study of the binding parameters. Journal of Molecular Biology, 344: 939-950.

   

3. Orly Laufman, Ron Ben Yosef, Noam Adir and Haim Manor (2005) Cloning and  characterization of the Schizosaccharomyces pombe homologs of the human protein Translin and the Translin-associated protein TRAX. Nucleic Acids Research 33: 4128-4139.

 

 4. Elad Eliahoo, Ron Ben Yosef, Laura Pérez-Cano, Juan Fernández-Recio, Fabian Glaser and Haim Manor (2010) Mapping of interaction sites of the Schizosaccharomyces pombe  protein Translin with nucleic acids and proteins: A combined molecular genetics and bioinformatics study. Nucleic Acids Research, 38, 2975-2989.