Lamm - פקולטה לביולוגיה Biology Faculty

Education/ Resume:

2007 Ph.D., Genetics and Cell Biology, Hebrew University of Jerusalem, Israel

2000 B.A., Computer Science. The Open University of Israel

Research Summary

We study fundamental epigenetics processes affecting gene expression and regulation. We are currently working on several projects: 1. RNA modification functions. 2. Understanding the interaction between RNAi and RNA editing processes. 3. Endogenous RNAi pathways in C. elegans. 4. Reliable quantification of gene expression in RNA-seq data.

Awards:

2016 The Bergmann Memorial Research Award, United States-Israel Binational Science Foundation

2012-2014 Taub Fellow – supported by the Taub Foundation

Key Publications

Ganem, N., Ben-Asher N., Manning A., Deffit S., Washburn M., Wheeler E., Yeo G., Ben-Naim Zgayer O., Mantsur E., Hundley H.A., and Lamm A.T. (2019) Disruption in A-to-I editing levels affect normal development more than a complete lack of editing in C. elegans. Cell Reports. 27(4):1244-1253.

Haas R, Ganem NS, Keshet A, Orlov A, Fishman A, Lamm AT. (2018) A-to-I RNA Editing Affects lncRNAs Expression after Heat Shock. Genes. 9(12).

Fishman A., Light D., and Lamm A.T. (2018) QsRNA-seq: A novel method for library preparation and quantification of small RNAs. Genome Biology. 19(1):113.

Ganem, N. and Lamm A.T. (2017) A-to-I RNA editing – thinking beyond the single nucleotide. RNA biology. Aug 18:1-5.

Ganem, N., Ben-Asher N. and Lamm A.T. (2017) In cancer, A-to-I RNA editing can be the driver, the passenger, or the mechanic. Drug Resistance Updates. 32:16-22.

Goldstein B., Agranat-Tamir L., Light D., Ben-Naim Zgayer O., Fishman A., and Lamm A.T. (2017) A-to-I RNA editing promotes developmental-stage specific gene and lncRNA expression. Genome Research. 27(3):462-470.

Ayelet Lamm