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UID:541@biology.technion.ac.il

DTSTART;TZID=Asia/Jerusalem:20141127T140000

DTEND;TZID=Asia/Jerusalem:20141127T150000

DTSTAMP:20210802T125836Z

URL:https://biology.technion.ac.il/en/seminars/dr-ilona-nudelman-a-postdoc
 toral-associate-at-the-laboratory-of-cellular-and-structural-biology-at-th
 e-rockefeller-university-2/

SUMMARY:Dr. Ilona Nudelman A postdoctoral associate at the Laboratory of Ce
 llular and Structural Biology at the Rockefeller University [No Categories
 ]
DESCRIPTION:Location:   \n Affiliation: \n Host:\n "NCDIR – National Cent
 er for Dynamic Interactome Research - Novel Technologies and Applications 
 for Study of Macromolecular Complexes"\nAbstract: \nThe vision of the Nati
 onal Center for Dynamic Interactome Research is to develop innovative and 
 dramatically new approaches for the detection\, isolation\, and analysis o
 f macromolecular complexes that will enable scientists to realize the full
  potential of the revolution brought about by genomics\, interdisciplinary
  research\, and proteomics technologies. In my talk I will present a small
  sample of our already established methodologies arsenal\, which enables u
 s to immuno-purify large amounts of endogenous macro-molecular complexes o
 f various complexities from virtually any organism. With these\, we are ab
 le to perform structural and functional studies using a multitude of techn
 iques\, including EM\, super-resolution and fluorescence microscopy\, cros
 s-linking\, MS\, SAXS and many others. These data serve as input into our 
 integrative modeling platform (IMP) which provides us with a functionally 
 informative pseudo-atomic model of the system in question. IMP has been us
 ed to demonstrate the strength of our integrative approach by application 
 to several challenging systems\, including the Nuclear Pore Complex\, Nup8
 4 complex\, 26S Proteasome\, ribosomes etc. Since our methodology has prov
 ed to be extremely successful\, we are interested in its dissemination amo
 ng the different scientific fields. One of our center’s main goals is to
  make our technologies readily available and provide training and support 
 in their use.\nמארח: פרופ' אריה אדמון\n admon@tx.technion
 .ac.il    \nההרצאה תתקיים באודיטוריום בבניין 
 הפקולטה לביולוגיה. 

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