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UID:1150@biology.technion.ac.il

DTSTART;TZID=Asia/Jerusalem:20230109T130000

DTEND;TZID=Asia/Jerusalem:20230109T140000

DTSTAMP:20230103T071116Z

URL:https://biology.technion.ac.il/en/seminars/dr-li-av-segev-zarko-depart
 ment-of-microbiology-and-immunology-at-stanford-university-school-of-medic
 ine/

SUMMARY:Dr. Li-av Segev Zarko -Department of Microbiology and Immunology at
  Stanford University School of Medicine. [No Categories]
DESCRIPTION:Location: Faculty Of Biology Auditorium  Dr. Li-av Segev Zarko 
 \n Affiliation: \n Host:Prof. Benjamin Podbilewicz  \n How One Eukaryotic 
 Cell Invades Another: Dissecting Invasion by Apicomplexa\nThe phylum Apico
 mplexa includes several of the most prevalent and important human eukaryot
 ic\npathogens\, such as Plasmodium spp.\, which causes malaria\, and Toxop
 lasma gondii\, which causes toxoplasmosis.\nHost cell invasion by these ob
 ligatory intracellular parasites is a remarkable and active process that\n
 depends on protein injection into the host cell and involves the coordinat
 ed action of apical organelles and\ncytoskeletal components. By coupling m
 olecular tools with state-of-the-art imaging techniques\, including\ncryog
 enic-electron microscopy\, we revealed striking conservation and differenc
 es in the invasion machinery\nused by Toxoplasma and Plasmodium. We identi
 fied mechanistic processes that promote protein secretion\nand resolved st
 ructural elements in the invasion machinery at subnanometer resolution\, p
 roviding new information\non how these important parasites accomplish the 
 essential step of invasion.\n\n&nbsp\;\n\n&nbsp\; 
LOCATION:Faculty Of Biology Auditorium

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