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UID:1151@biology.technion.ac.il

DTSTART;TZID=Asia/Jerusalem:20230116T130000

DTEND;TZID=Asia/Jerusalem:20230116T140000

DTSTAMP:20230109T131549Z

URL:https://biology.technion.ac.il/en/seminars/dr-tanita-wein-department-o
 f-molecular-genetics-at-the-weizmann-institute-of-science/

SUMMARY:Dr. Tanita Wein -Department of Molecular Genetics at the Weizmann I
 nstitute of Science [No Categories]
DESCRIPTION:Location: Faculty Of Biology Auditorium  Dr. Tanita Wein\n Affi
 liation: \n Host:Prof. Benjamin Podbilewicz  \n Understanding the ancient 
 evolution and function of innate immunity\n\nThe human innate immune syste
 m has long been considered the result of extensive evolutionary innovation
 s in metazoans. However\, this dogma has now been challenged. Recent studi
 es show that essential components of the cell-autonomous innate immune sy
 stem have ancient evolutionary roots in prokaryotic defense systems that p
 rotect bacteria from phages. Nonetheless\, while we know that certain comp
 onents of the innate immune response were inherited from prokaryotes\, a l
 arge portion of functional and mechanistic diversity across the tree of l
 ife remains so far uncharted territory. Therefore\, in my future research\
 , I will explore the evolutionary links between prokaryotic and eukaryotic
  immune systems. For this\, I aim to focus on evolutionary transitions su
 ch as lifestyle changes in bacteria and basal eukaryotes that have the pot
 ential to elucidate the evolutionary history and function of central innat
 e immune components. Utilizing a bottom-up approach harnessing the diversi
 ty of microbes will lead to the discovery of novel concepts\, functions a
 nd processes in immunity across all domains of life including plants and a
 nimals.\n\n&nbsp\;\n\n&nbsp\; 
LOCATION:Faculty Of Biology Auditorium

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