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UID:1093@biology.technion.ac.il

DTSTART;TZID=Asia/Jerusalem:20220726T130000

DTEND;TZID=Asia/Jerusalem:20220726T133000

DTSTAMP:20220713T072620Z

URL:https://biology.technion.ac.il/en/seminars/m-sc-graduate-seminar-susie
 -altalef-mishaan/

SUMMARY:M.Sc. Graduate Seminar-Susie Altalef Mishaan [No Categories]
DESCRIPTION:Location:   \n Affiliation: \n Host:\n  Throughoutthe last num
 ber of years\, the non-protein-coding portion of the human genomehas gone 
 from being considered “junk DNA” to “hot spots” in the area of lif
 escience. Genome-wide transcriptome studies indicate that this portion cov
 ers75-90% of the genome\, whereas only 2% of the human genome comprisespro
 tein-coding genes. The non-protein-coding areas in the genome generatenon
 -coding RNAs (ncRNAs) that are subsequently divided according to theirfunc
 tion and size. In the human genome\, the majority of these ncRNAs areclass
 ified as long non-coding RNAs (lncRNAs)\, transcripts of more than 200nucl
 eotides that are not translated into proteins. lncRNAs have been foundto 
 be involved in many biological processes\, such as in chromatinmodificatio
 ns. Despite their apparent importance\, only a handful oflncRNAs have bee
 n discovered and characterized\; their function and mechanismsof action re
 main elusive. My research objective was to identify andcharacterize lncRNA
 s\, especially those that are hypothesized to be functionaland work in a s
 equence-specific trans-regulating manner.  

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