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UID:1269@biology.technion.ac.il

DTSTART;TZID=Asia/Jerusalem:20250303T130000

DTEND;TZID=Asia/Jerusalem:20250303T133000

DTSTAMP:20250226T142355Z

URL:https://biology.technion.ac.il/en/seminars/m-sc-graduate-seminar-tal-i
 fargan-the-faculty-of-data-and-decision-sciences/

SUMMARY:M.Sc. Graduate Seminar-Tal Ifargan (The Faculty of Data and Decisio
 n Sciences) [No Categories]
DESCRIPTION:Location: Hybrid- in the Faculty Auditorium/ZOOM:https://techni
 on.zoom.us/j/95712138406  Tal Ifargan\n Affiliation: \n Host:Prof. Kishony
  Roy \n AI-Driven Research and Trait Aware Representations of Medical Diag
 nostics\n\n&nbsp\;\n\nAbstract\n\n&nbsp\;\n\nThis seminar is devoted to tw
 o separate projects:\n\n&nbsp\;\n\nAs AI promises to accelerate scientific
  discovery\, it remains unclear whether AI systems can perform fully auton
 omous research and whether they can do so while adhering to key scientific
  values\, such as transparency\, traceability and verifiability. Mimicking
  human scientific practices\, we built data-to-paper\, an automation platf
 orm that guides interacting LLM agents through a complete stepwise researc
 h process\, from annotated data to comprehensive research papers\, while p
 rogrammatically back-tracing information flow\, resulting in “data-chain
 ed” manuscripts. Testing the platform on diverse datasets\, it produced 
 autonomously correct papers in 80%-90% of runs for simple datasets and res
 earch goals\, yet human interventions became critical for more complex tas
 ks. Our work demonstrates a potential for AI-driven acceleration of scient
 ific discovery in data-driven research and beyond\, while setting through 
 “data-chaining” a new standard for verifiability and traceability for 
 the coming era of AI-driven science.\n\n&nbsp\;\n\nElectronic health recor
 ds offer significant potential for uncovering trait-specific patterns and 
 advancing personalized medicine. Various methods\, mainly borrowed from na
 tural language processing\, have been proposed to represent International 
 Classification of Diseases (ICD) codes\, yet these approaches often yield 
 representations that are difficult to quantify and primarily serve predict
 ive tasks. Here\, we present TAR—a method for Trait-Aware Representation
 s of ICD codes implemented as a modified skip-gram model and demonstrate i
 ts ability to explore sex-specific differences in medical diagnostics\, a 
 topic often overlooked in prior literature. In collaboration with Maccabi 
 Healthcare Services\, we trained TAR on 25 years of data from 1.3 million 
 patients\, revealing sex-dependent dynamics of aging. In addition\, the le
 arned embeddings encode the concept of sex as a distinct direction. Overal
 l\, TAR presents sex-specific diagnostic differences\, and is readily exte
 ndable to other phenotypic traits\, offering a versatile tool for broader 
 biomedical discovery. 
LOCATION:Hybrid- in the Faculty Auditorium/ZOOM:https://technion.zoom.us/j/
 95712138406

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