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UID:1359@biology.technion.ac.il

DTSTART;TZID=Asia/Jerusalem:20260324T133000

DTEND;TZID=Asia/Jerusalem:20260324T140000

DTSTAMP:20260323T123258Z

URL:https://biology.technion.ac.il/en/seminars/msc-graduate-seminar-nada-s
 widan/

SUMMARY:Msc Graduate Seminar-Nada Swidan [No Categories]
DESCRIPTION:Location: Hybrid - in the Faculty Auditorium /ZOOM: https://tec
 hnion.zoom.us/j/96483815055  Nada Swidan\n Affiliation: Associate Prof. Ay
 elet Lamm\n Host:\n Characterizing A-G Mismatch Signatures Associated with
  A-to-I RNA Editing and m6A in C. elegans\n\nRNA molecules can undergo che
 mical modifications that influence how they are processed and regulated. U
 sing Caenorhabditis elegans as a model system\, we analyze RNA sequencing 
 datasets to investigate different types of RNA modifications. Focusing on 
 A-to-I RNA editing\, we identify candidate editing sites in mature and pre
 cursor microRNAs and examine their expression dynamics during embryonic de
 velopment. RNA sequencing data frequently contain nucleotide mismatches re
 lative to the reference genome\; while some can be explained by A-to-I RNA
  editing\, many remain unexplained. We therefore analyze transcriptome-wid
 e data to explore whether characteristic mismatch patterns in mRNA reads m
 ay reflect signatures associated with m6A modification. Together\, these a
 nalyses provide insight into how RNA modifications shape RNA regulation an
 d suggest potential avoidance between different RNA modification pathways.
 athways. 
LOCATION:Hybrid - in the Faculty Auditorium /ZOOM: https://technion.zoom.us
 /j/96483815055

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DTSTART:20251026T010000

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