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UID:1330@biology.technion.ac.il

DTSTART;TZID=Asia/Jerusalem:20251210T130000

DTEND;TZID=Asia/Jerusalem:20251210T133000

DTSTAMP:20251109T094744Z

URL:https://biology.technion.ac.il/en/seminars/msc-graduate-seminar-netali
 -snof/

SUMMARY:MSc Graduate Seminar- Netali Snof [No Categories]
DESCRIPTION:Location: Hybrid - in the Faculty Auditorium /ZOOM:  https://te
 chnion.zoom.us/j/91065669587   Netali Snof\n Affiliation: \n Host:Associat
 e Prof. David Meiri  \n Enhancement of Human CD8+ T Cell Cytotoxicity by e
 xtracts from Amanita muscaria and Psilocybin-Producing Fungi13\nPsychoacti
 ve fungi contain diverse metabolites with potential immunomodulatory prope
 rties. Here we investigated metabolites from two distinct pharmacological 
 classes: serotonergic tryptamines from psilocybin-producing fungi and glut
 amatergic compounds from Amanita muscaria. In a screen of 38 mushroom ext
 racts\, we identified several that enhanced the function of Cytotoxic T L
 ymphocytes. The A. muscaria extract was superior to all others\, and sign
 ificantly effective in increasing the levels of the cytotoxic protein Gran
 zyme B. These findings highlight the potential of metabolites from psychoa
 ctive fungi as an underexplored source of novel immunomodulatory agents. 
LOCATION:Hybrid - in the Faculty Auditorium /ZOOM:  https://technion.zoom.u
 s/j/91065669587

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