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UID:1068@biology.technion.ac.il

DTSTART;TZID=Asia/Jerusalem:20220309T133000

DTEND;TZID=Asia/Jerusalem:20220309T140000

DTSTAMP:20220713T072649Z

URL:https://biology.technion.ac.il/en/seminars/msc-graduate-seminar-reemy-
 ali-nasser/

SUMMARY:MSc Graduate Seminar-Reemy Ali Nasser [No Categories]
DESCRIPTION:Location:   \n Affiliation: \n Host:\n Early-life experiencere-
 organizes neuromodulatory regulation of developmental patterns of behavior
 and individuality   Early-life experiences may promote robust and long-
 lastingbehavioral outputs within populations\, but also patterns of behavi
 oralresponses that are variable among individuals\, even when initially ex
 posed tothe same early stimulus. In my project\, I studied how early-life 
 starvationmodifies behavior and inter-individual diversity across developm
 ent bymonitoring C. elegans individual behaviors continuously throughout a
 lldevelopmental stages\, at high spatiotemporal resolution and under tight
 lycontrolled conditions. My results show that early starvation generates d
 istinctand discontinuous behavioral effects across different life stages. 
 Bothdopamine and serotonin mediate stage-specific behavioral responses to 
 earlystarvation. While serotonin promotes behavioral sensitivity during ea
 rly andlate stages of development\, dopamine buffers the behavioral respon
 se viaspecific receptors during intermediate stages. Moreover\, by quantif
 yinginter-individual behavioral diversity across development within stress
 ed andnon-stressed populations\, I found that neuromodulators restrict alt
 erations inindividuality levels by stress. My research reveals that early-
 life experiencesgenerate complex neuromodulatory regulation of behavioral 
 patterns andindividuality across development.  

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