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UID:1069@biology.technion.ac.il

DTSTART;TZID=Asia/Jerusalem:20220316T130000

DTEND;TZID=Asia/Jerusalem:20220316T140000

DTSTAMP:20220303T090135Z

URL:https://biology.technion.ac.il/en/seminars/phd-graduate-seminar-ben-ba
 r-sade/

SUMMARY:PhD Graduate Seminar-Ben Bar-Sade [No Categories]
DESCRIPTION:Location:   \n Affiliation: \n Host:\n Underlying mechanisms of
  re-programingreproduction following early life adversityA high burden of 
 inflammatory diseasewas correlated with later puberty onset and earlier me
 nopause in a study ofmigrant women\, possibly suggesting an adaptive respo
 nse to optimizereproductive success. We combined data from that human stud
 y with anappropriate mouse model to investigate the molecular mechanisms i
 nvolved inthis response. We found altered DNA methylation and expression l
 evels ofseveral genes in reproductive tissues\, and showed direct effects 
 of thesealterations on reproductive function. Understanding the molecular 
 eventsinduced by early-life stress and identification these stable epigene
 tic marksmight be used to help assess a woman’s reproductive status and 
 predict the length of herreproductive lifespan.Time:  Tuesday\, March 16\,
  2022\, 13:00pm. Place: Hybrid- in the Faculty Auditorium / ZOOM:https://t
 echnion.zoom.us/j/98476893981 

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DTSTART:20211031T010000

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