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UID:1004@biology.technion.ac.il

DTSTART;TZID=Asia/Jerusalem:20211027T130000

DTEND;TZID=Asia/Jerusalem:20211027T140000

DTSTAMP:20211118T110055Z

URL:https://biology.technion.ac.il/en/seminars/phd-graduate-seminar-rina-b
 en-el-october-27th-1300pm-2/

SUMMARY:PhD Graduate Seminar-Rina Ben-El- October 27th 13:00PM [No Categori
 es]
DESCRIPTION:Location:   \n Affiliation: \n Host:\n “Computational approac
 h to identify new roles for long non-coding RNAs involved in pluripotency 
 and differentiation”Recently long non coding RNAs (lncRNAs) have emerged
  as regulators of pluripotency and differentiation\, however their contrib
 ution to specific lineage commitment is yet largely unknown. We generated 
 RNA-seq data\, in human induced Pluripotent Stem cells (iPSc) and applied 
 a network approach to help assign lncRNAs with unknown functions to these 
 processes. We found many differentially expressed lncRNAs highly co-expres
 sed with known markers of differentiation. These results were validated wi
 th ChiP-seq data suggesting a possible regulatory relationship between the
  TFs and the lncRNAs.  

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