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UID:1220@biology.technion.ac.il

DTSTART;TZID=Asia/Jerusalem:20240625T130000

DTEND;TZID=Asia/Jerusalem:20240625T140000

DTSTAMP:20240501T193636Z

URL:https://biology.technion.ac.il/en/seminars/phd-graduate-seminar-rina-z
 uchman/

SUMMARY:PhD Graduate Seminar- Rina Zuchman [No Categories]
DESCRIPTION:Location: Hybrid- in the Faculty Auditorium/ZOOM: https://techn
 ion.zoom.us/j/96303584862    Rina Zuchman\n Affiliation: \n Host:Prof. Ben
 jamin A. Horwitz\n Novel fungal MAP kinase signalling in response to a hos
 t plant small-molecule signal in the Cochliobolus-maize interaction\n\nOur
  study aims to investigate the relationship between fungi and their plant 
 hosts during infection\, focusing on the maize pathogen C. heterostrophus
 \, which serves as a model for necrotrophic plant pathogens. Analysis of i
 nfected leaves at various stages of disease development\, using RNA-seq an
 d fluorescence microscopy\, uncovered a correlation between fungal hyphal 
 development\, necrotrophic gene expression\, and plant defense mechanisms.
  Notably\, the host plant upregulates defense-related genes early in infec
 tion\, particularly those involved in phenolic acid biosynthesis. When ger
 minating spores are exposed to ferulic acid (FA)\, a phenolic compound abu
 ndant in the host plant\, the stress-activated MAP kinase Hog1 is\, surpri
 singly\, dephosphorylated and sequestered in cytoplasmic foci rather than 
 phosphorylated and accumulated in the nucleus\, as expected in stress resp
 onses. This unique signalling pathway may play a role in attenuating cell 
 death induced by plant defense compounds like FA. Our findings provide ins
 ights into the dynamics of pathogen cell death\, survival\, and proliferat
 ion within lesions\, while also shedding light on stress responses mediate
 d by MAP kinases. 
LOCATION:Hybrid- in the Faculty Auditorium/ZOOM: https://technion.zoom.us/j
 /96303584862 

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