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UID:1096@biology.technion.ac.il

DTSTART;TZID=Asia/Jerusalem:20220405T143000

DTEND;TZID=Asia/Jerusalem:20220405T153000

DTSTAMP:20220713T072649Z

URL:https://biology.technion.ac.il/en/seminars/prof-max-heiman-department-
 of-genetics-at-harvard-medical-school-and-division-of-genetics-and-genomic
 s-boston-childrens-hospital-ma/

SUMMARY:Prof. Max Heiman\, Department of Genetics at Harvard Medical School
 \, and Division of Genetics and Genomics\, Boston Children's Hospital\, MA
  [No Categories]
DESCRIPTION:Location:   \n Affiliation: \n Host:\n Title:  Tracking the d
 evelopment and assembly of single cellsAbstract:  While high-throughput m
 ethods provide a sweepingbirds-eye view of development\, different insight
 s can be gained by zooming into study how a single cell develops.  This i
 s especially true in C.elegans\, where each cell's identity\, morphology\,
  and connections are highlystereotyped.  Here\, we follow the specificati
 on and assembly of a singleneuron-glia pair in C. elegans.  First\, we ex
 amine how someprogenitors escape lineage fate restriction in order to unde
 rgo convergentdifferentiation\, giving rise to a glial cell type that is i
 dentical to thatproduced by unrelated lineages.  Second\, we show how a s
 ingle neuron pairsoff with one of these glial cells by using its cilium to
  mediate cell-celladhesion. In-depth analysis of individual gene functions
  in single cellsprovides a counterpoint to the trend towards massive syste
 ms-level descriptionsof entire cell populations.Host: Sagi Levy 

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