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UID:1097@biology.technion.ac.il

DTSTART;TZID=Asia/Jerusalem:20220407T123000

DTEND;TZID=Asia/Jerusalem:20220407T130000

DTSTAMP:20220713T072649Z

URL:https://biology.technion.ac.il/en/seminars/sc-graduate-seminar-jordan-
 mc-carthy/

SUMMARY:Sc Graduate Seminar- Jordan Mc Carthy [No Categories]
DESCRIPTION:Location:   \n Affiliation: \n Host:\n Place: hybrid- inthe Fac
 ulty Auditorium/ZOOM:https://technion.zoom.us/j/93473479861The role of pre
 gnancy in skin regenerationAbstract: The physiology of mammalian skin chan
 gesdramatically during pregnancy due to immunological\, metabolic\, and ho
 rmonalshifts. Estrogens are major regulators of these homeostatic changes 
 and arealso known to affect the hair cycle. We have found that during preg
 nancy\, hairfollicle stem cells (HFSCs) become active and initiate hair gr
 owth. This cellcycle entry is dependent upon estrogen signaling. In this s
 tate\, upon woundinfliction HFSCs vastly contribute to the repair process.
  Importantly\, we findthat skin repair and hair follicle regeneration is i
 mproved during pregnancy.Taken together our findings could potentially giv
 e rise to novel therapeuticavenues for regenerative medicine.  

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