Postdoctoral Fellow, Department of Genetics school of medicine, Stanford University, 2023
Ph.D., Department of Biomolecular Sciences, Weizmann Institute of Science, 2015
MSc, Department of Human Molecular Genetics and Biochemistry, Tel-Aviv University, 2008
B.Sc., Life Sciences, The Hebrew University of Jerusalem, 2005
Neuronal cell death, dendrite and axonal degeneration are active, tightly controlled processes of self-destruction. These processes take place normally during development of the nervous system and abnormally in neurodegenerative diseases such as Alzheimer, Parkinson and Amyotrophic Lateral Sclerosis.
In our lab, we seek to understand the molecular processes that drive these neurons, axons and dendrites to degeneration and their unique selective vulnerability in different diseases. Answering this fundamental question will reveal therapeutic targets for degenerative disorders and provide insight into the cellular and molecular mechanisms of neuronal, axonal and dendrites degeneration and survival.
2024 Zuckerman Faculty Scholar
2022 Careers through Mentoring in Omics and Data for Early-stage Investigators (Career MODE) Scholarship2021 Sammy Kuo Award for Neuroscience, Second place
2020 Barber ALS Research Award
2017 European Molecular Biology Organization (EMBO) long-term Fellowship Award
2017 SSSI-Muscular Dystrophy Association (MDA) Fellowship Award
2017 Larry L. Hillblom Foundation (LLHF) Advancing Medical Knowledge Postdoctoral Fellowship Award
2016 The Dean’s Postdoctoral Fellowship at the Stanford School of Medicine.
2007 Adams Super Center for Brain Research, Scholarship.
Maor-Nof M*, Shipony Z, Lopez-Gonzalez R, Nakayama L, Zhang YJ, Couthouis J, Blum JA, Castruita PA, Linares GR, Ruan K, Ramaswami G, Simon DJ, Nof A, Santana M, Han K, Sinnott-Armstrong N, Bassik MC, Geschwind DH, Tessier-Lavigne M, Attardi LD, Lloyd TE, Ichida JK, Gao FB, Greenleaf WJ, Yokoyama JS, Petrucelli L, Gitler AD*. p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR). Cell. 184(3):689-708. (2021)
* Corresponding Author
• Spotlight A Role for p53 in c9ALS/FTD? Fare CM, Shorter J. Trends Genet. S01689525(21)00026- 3. (2021)
• News p53 is a central regulator driving neurodegeneration in mice. Jack Williamson. The Lancet Healthy Longevity. S2666-7568(21)00034-9. (2021)
Maor-Nof M, Romi E, Sar Shalom H, Ulisse V, Raanan C, Leshkowitz D, Lang R and Yaron. Axonal degeneration is regulated by a transcriptional program that coordinates expression of pro- and anti- degenerative factors. Neuron. 92(5):991-1006. (2016).
• Highlight Nature Reviews Neuroscience Neural development: Balancing the pruning programmes. 18(1):4 (2017).
The Maor-Nof lab is actively recruiting at all levels!
