Schuster - פקולטה לביולוגיה Biology Faculty

Education/ Resume:

Ph.D., 1987, Hebrew University of Jerusalem
B Sc, 1982, Hebrew University of Jerusalem

Research Summary

We study the molecular mechanisms of how plants and algae protect the photosynthetic machinery from photoinhibition, the damages caused by extreme high light (photoinhibition).

We also study the molecular mechanism of RNA polyadenylation and degradation in different organisms including prokaryotes, archaea, chloroplast, human mitochondria and nuclear encoded RNA; the mechanism of post-transcriptional regulation of mRNA stability; RNA maturation and interaction on mRNA with proteins; control of gene expression in the chloroplast and human mitochondria.

We also study the control of gene expression in the chloroplast. Mainly at the level of RNA metabolism, how the RNA half-life is determined and the molecular mechanisms of polyadenylation and degradation.

Awards:

Henry Goldberg Academic Chair.
Hershel Rich Innovation Prize
Distinguished Lecturer Award at the Technion.

Key Publications

Lisitsky, I., Klaff, P. and Schuster, G. (1996) Addition of destabilizing poly(A)-rich sequences to endonuclease cleavage sites during the degradation of chloroplast mRNA. Natl. Acad. Sci. USA 93: 13398-13403.

Portnoy, V., Evguenieva-Hackenberg, E., Klein, F., Walter, P., Lorentzen, E., Klug, G. and Schuster, G. (2005) RNA polyadenylation in Archaea: Not observed in Haloferax while the exosome polyadenylates RNA in Sulfolobus. EMBO Rep. 6: 1188-1193.
Slomovic, S., Laufer, D., Geiger, D. and Schuster, G. (2006) Polyadenylation of ribosomal RNA in human cells. Nucl. Acid. Res. 34: 2966-2975.
Slomovic S., Fremder E., Staals R., Pruijn G. and Schuster G. (2010) Addition of poly(A) and poly(A)-rich tails during RNA degradation in the cytoplasm of human cells. Proc. Natl. Acad. Sci. USA 107: 7407-12.
Larum, S., Faris, S., Schuster, G. and Adir, N (2010) Engineering of an alternative electron transfer path in Photosystem II. Proc. Natl. Acad. Sci. (USA), 107: 9650-5
Levy, S., Allerston, CK., Liveanu, V., Haviv, MR., Gileadi. O. and Schuster, G. (2016) Identification of LACTB2, a metallo-b-lactamase protein, as a human mitochondrial endoribonuclease. Nucl. Acid Res. 44:1813-32.
Saper, G., Kallmann, D., Conzuelo, F., Zhao, F., Toth, T., Liveanu, V., .Meir, M., Szymanski, J., Aharoni, A., Schuhmann, W., Rothschild^,A., Schuster, G.,^* and Adir, N^* (2018) Live cyanobacteria produce photocurrent and hydrogen using both the respiratory and photosynthetic

Gadi Schuster