Ron-Harel - פקולטה לביולוגיה Biology Faculty

Education/ Resume

2018

Assistant Professor, Faculty of Biology, Technion.

2010-2017

Postdoctoral research fellow, Department of Cell Biology, Harvard Medical School, Boston, USA. Advisor: Prof. Marcia Haigis.

2004-2010

PhD (direct track) Life Sciences, Department of Neurobiology, The Weizmann Institute of Science, Rehovot, Israel. Advisor: Prof. Michal Schwartz

2000-2003

B.Sc Molecular Biochemistry, Faculty of Chemistry, Technion, Israel Institute of Technology, Haifa, Israel. Summa Cum laude

Research Summary

My research focuses on immune aging, investigating how host aging drives immune dysfunction and aiming to uncover the metabolic and molecular mechanisms underlying changes in adaptive immunity across the lifespan.

Awards

2020 Catalyst award, Healthy Longevity Global Competition, US National Academy of Medicine

2019 Outstanding Early Career Investigator Team Presentation, NYAS Interstellar Initiative.

2018 Sabri Ulker Early Career Award, Translational Immunomatabolism Cell Symposia.

2011 Award of excellence granted by the “National Postdoctoral Award Program for Advancing Women In Science”

2011 EMBO long-term postdoctoral research fellowship

2010 Dean’s award for academic excellence and scientific accomplishments, Weizmann institute of science.

2006 The Clore Israel Foundation scholarship for outstanding PhD candidates.

Key Publications

David Ezuz, Heba Ombashe, Lana Watad, Akmaral Rakhymzhanova, Satyarth Pandey, Orna Atar, Esther G. Meyron-Holtz and Noga Ron-Harel. “Heme and iron toxicity in the aged spleen impairs T-cell immunity through iron deprivation”. Nature Aging. 2025; 5(11): 2247-2262.; doi: 10.1038/s43587-025-00981-4

Noga Ron-Harel, Jonathan Ghergurovich, Giulia Notarangelo, Martin W LaFleur, Yoshiki Tsubosaka, Arlene H. Sharpe^*, Joshua D. Rabinowitz^* and Marcia C. Haigis^*. “T cell activation depends on cellular alanine”. Cell Reports, 2019, 28(12), 3011-3021.e4.

Noga Ron-Harel, Giulia Notarangelo, Jonathan Ghergurovich, Joao A. Paulo, Peter T. Sage, Daniel Santos, F. Kyle Satterstrom, Steven Gygi, Joshua D. Rabinowitz, Arlene H. Sharpe and Marcia C. Haigis. “Defective respiration and one-carbon metabolism contribute to impaired naïve T cell function in aged mice”. PNAS, 2018, 115(52), 13347-13352.

Noga Ron-Harel, Daniel Santos, Jonathan Ghergurovich, Peter T. Sage, Anita Reddy, Scott B. Lovitch, Noah Dephoure, F. Kyle Satterstrom, Michal Sheffer, Jessica B. Spinelli, Steven Gygi, Joshua D. Rabinowitz, Arlene H. Sharpe and Marcia C. Haigis. “Mitochondrial biogenesis and proteome remodeling promote one-carbon metabolism for T cell activation” Cell Metabolism, 2016 24(1): 104-117.

Open Positions

We are always looking for highly motivated postdocs and graduate students to join us.