The lab research is inherently interdisciplinary: we use physics considerations and computer simulations, while working in close collaboration with experimental biologists in an effort to create models that are relevant to understanding the actual biological systems. In contrast with information-focused theoretical biology, we study the “blue collar”, mechanical, role of proteins and lipids.
Research Summary
We construct theoretical, physics-based models for the formation, shaping and function of sub-cellular structures. Primarily, we study the morphology of membrane surfaces in the endoplasmic reticulum (ER), self-arrangement and force production in the cytoskeleton, and the interplay between proliferation and mechanics in multi-cellular systems.
