Mandel-Gutfreund Lab Summer Project

Our lab integrates experimental and computational biology approaches to explore the regulation of gene expression in human stem cells, in pluripotency, differentiation, and during viral infections. The projects in the lab include experimental work using high-throughput technologies, big data analysis, and the development of novel technology and computational tools.

During the summer we invite you to participate in one of the following projects:

• Experimental Project: Screening for novel dual DNA and RNA binding proteins that mediate the cross-talk between transcriptional and post-transcriptional regulation in human stem cells.
• Experimental Project: Studying changes in gene expression regulation in single cells from amniotic fluids from pregnancies of women infected by the Human Cyto Megalo virus (CMV)
• Computational project: Studying the interaction network between proteins and long-non-coding RNAs (lncRNAs) involved in human embryonic stem cells.
• Computational project: Developing a computational approach to analyze isoform changes during stem cell differentiation and in viral infections based on single-cell RNA–sequencing data