Ariel Kaplan

Ariel Kaplan

Education/ Resume:

2006-2010: Postdoctoral fellow, University of California, Berkeley.

2004-2006: Postdoctoral fellow, Weizmann Institute of Science.

1999-2004: PhD, Weizmann Institute of Science

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Research Summary

We are a single-molecule biophysics lab, using advanced optical tools to study the interactions between proteins and DNA that are at the heart of the regulation of gene expression. In particular, we are interested in the structure and dynamics of chromatin, binding of transcription factors to DNA and the function of polymerases and helicases.

Key Publications
  • S. Rudnizky*, H. Khamis*, O. Malik, P. Melamed, and A. Kaplan, “The base pair-scale diffusion of nucleosomes modulates binding of transcription factors”, PNAS 116, 12161 (2019).
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Recent Publications:

S. Rudnizky, H. Khamis, Y. Ginosar, E. Goren, P. Melamed and A. Kaplan, “Extended and dynamic linker histone-DNA interactions control chromatosome compaction”, bioRxiv https://doi.org/10.1101/2020.10.10.334474 (2020)

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Open Positions

We are always looking for talented MSc and PhD students to join us. Students with a background in Physics, Biology, Chemistry or Engineering are wellcome to apply.

Postdoctoral applicants must have a PhD degree, a strong publication record and demonstrated ability to work independently. Expertise in single-molecule and/or bulk biophysics, molecular biology or microscopy is an advantage. However, an open mind, good hands, and a record of success in your PhD are the only requirements.

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