Savaldi-Goldstein - פקולטה לביולוגיה Biology Faculty

Education

2008 – Postdoc, Salk Institute (mentor: Prof. Joanne Chory)
2003 – PhD, Weizmann Institute of Science (mentor: Prof. Robert Fluhr)

Research Summary

Our lab investigates fundamental aspects that regulate plant growth and development. Using both classical and state-of-art tools, we study the role of hormonal signaling, tissue identity, and mechanical constraints, that together dictate a developmental output. In parallel, we investigate how these processes are tuned by distinct environmental conditions.

Awards

The Cooper Prize for Academic Excellence
Landau Fellow in the Technion program “Leaders in Science and Technology”
Yigal Alon Fellowship for outstanding starting investigators awarded by the Israeli Council for Higher Education
NSF travel award
BARD Postdoctoral Fellowship

Key Publications

Ackerman-Lavert, M., Fridman, Y., Matosevich, R., Khandal, H., Friedlander-Shani, L., Vragovic, K., Ben El, R., Horev, G., Tarkowska, D., Efroni, I., and Savaldi-Goldstein, S. Auxin requirements for a meristematic state in roots depend on a dual brassinosteroid function. Curr Biol. (2021).

Singh, A.P., Fridman, Y. , Holland N., Ackerman-Lavert, M.; Zananiri R., Jaillais, Y, Henn A. and Savaldi-Goldstein, S. Interdependent nutrient availability and steroid hormone signals facilitate root growth plasticity, Dev Cell, 46, 59-72 (2018).

Vragović, K.*, Sela, A.*, Friedlander-Shani, L., Fridman, Y., Hacham, Y., Holland, N., Bartom, E., Mockler, T.C. and Savaldi-Goldstein, S. Translatome analyses capture of opposing tissue-specific brassinosteroid signals orchestrating root meristem differentiation. Proc Natl Acad Sci U S A 112, 923-928 (2015).

Fridman, Y., Elkouby, L., Holland, N., Vragovic, K., Elbaum, R., and Savaldi-Goldstein. S. Root growth is modulated by differential hormonal sensitivity in neighboring cells. Genes & Dev 28, 912-920 (2014).

Hacham, Y., Holland, N., Butterfield, C., Ubeda-Tomas, S., Bennett, M.J., Chory, J. and Savaldi-Goldstein, S. Brassinosteroid perception in the epidermis controls root meristem size. Development 138, 839-48 (2011).

Savaldi-Goldstein, S., Peto, C. and Chory, J. The epidermis both drives and restricts plant shoot growth. Nature 446, 199-202 (2007).

Sigal Savaldi-Goldstein