Exploring How Antigen Type Shapes CAR T Cell Sensitivity and Function
CAR T cell therapy has revolutionized cancer treatment, yet challenges remain in targeting solid tumors.
This research directly compares CAR T cells targeting two different types of antigens: a surface protein and a peptide MHC complex, using a fully controlled system.
The study reveals how antigen type influences CAR T cell sensitivity and function, offering new insights for improving next-generation cancer immunotherapies.
