Seminars

Transcription Factors-RNA interaction: a new layer of cellular regulation Gene expression is a complex process tightly regulated by various proteins, including DNA-binding proteins (DBPs) and RNA-binding proteins (RBPs). However, little... →

The ins and outs of meristem function and shape   Abstract:   Growth extent and direction determine cell and whole-organ architecture. How they are spatio-temporally coordinated across distinct cell types... →

A dual role of RBM42 in modulating splicing and translation during DNA damage response: A spotlight on CDKN1A/p21 gene   Abstract p53-mediated cell cycle arrest during DNA damage is dependent... →

Precise patterning in the inner ear   Abstract:   Precise periodic organization of cells is required for the function of many organs and tissues. It is often unclear, however, how... →

Estrogen Receptor Modulation by a Newly-Identified Phytocannabinoid in a Preclinical Model of Breast Cancer Breast cancer is made up of different subtypes that respond differently to treatments. Tumors that express... →

Characterization of Peroxismoal Proteins Changes in Response to Stress   Peroxisomes are organelles with a single bilayer membrane that encloses a soluble matrix space. Their importance is highlighted by the... →

Anti-cancer compounds from East Mediterranean seaweeds This project is aimed to study the anti-cancer effect of the East Mediterranean seaweeds to point out seaweeds of interest for future investigation and... →

  ISG15 and ISGylation at the ribosome: mechanistic analysis, innate immune response, and impact on translation   The innate immune response is the first line of defense against all pathogens.... →

Developing a single molecule approach to selective ribosome profiling   mRNA-protein interactions are at the center of the translation process. Ribosome-associated factors, from modifying enzymes to molecular chaperones, play a... →

Understanding the turnover of the truncated form of mutant ubiquitin UBB+1, UBBG76Y Ubiquitin is a 76 amino acid molecule that labels proteins for degradation. Its C-terminus at 76 glycine is... →

Reference-based deep examination of single-cell RNA-seq clusters Identifying the biological state of each single cell is arguably the most challenging task in scRNA-seq data analysis. Doing so requires bridging the... →

Title: comprehensive terminomic characterization of biological systems. Seminar abstract: Protein termini carry valuable information related to protein activity, localization, interaction and stability. Learning these various properties can be detrimental to... →

  Decreased melanoma CSF-1 secretion by Cannabigerol treatment reprograms regulatory myeloid cells and reduces tumor progression   During solid tumor progression, the tumor microenvironment (TME) evolves into a highly immunosuppressive... →

An Internal Model of Sensorimotor Context in Freely Swimming Electric Fish Internal models that predict the sensory consequences of motor actions are vital for sensory, motor, and cognitive functions. However,... →

Immunomodulation of EAE with Antibodies Targeting Autoreactive T-Cell Epitopes   Multiple sclerosis (MS) is a demyelinating autoimmune disease influencing more than 2.5 million people around the world. Damage caused in... →

The UPRmt coordinates mitochondrial network expansion and peroxisome biogenesis in the model organism Caenorhabditis elegans As organisms develop, individual cells generate mitochondria and peroxisomes to fulfill their physiological requirements. A... →

Oligodendrocyte plasticity in cognitive aging and neurodegeneration Abstract Recent understanding of how the systemic environment shapes the brain throughout life has led to numerous intervention strategies to slow brain aging.... →

Posters that were chosen as excellent in the departmental research days, will be presented by the graduate students. A panel of judges will choose the winning posters. A “Crowd Favorite”... →

Understanding the ancient evolution and function of innate immunity The human innate immune system has long been considered the result of extensive evolutionary innovations in metazoans. However, this dogma has... →

Study of Antigen Presentation and Antigen-Specific Immunomodulation in Multiple Sclerosis by T cell Receptor-mimic Antibodies During autoimmune diseases, like Multiple Sclerosis (MS), the immune system is downregulated in a non-specific... →

How One Eukaryotic Cell Invades Another: Dissecting Invasion by Apicomplexa The phylum Apicomplexa includes several of the most prevalent and important human eukaryotic pathogens, such as Plasmodium spp., which causes... →

Estrous cycle and Egg release resets inspired by neurodynamics in the circadian pacemaker   Jet lag and shift work disrupt the menstrual cycle and decrease fertility. The circadian pacemaker, the... →

The third lecture in the "Science Talk on the Bar" series of the Faculty of Biology About: • Is cannabis the antibiotics of the 21st century? • How many patients... →

Archaeal origins of gamete fusion Sexual reproduction consists of genome reduction by meiosis and subsequent gamete fusion. Fusexins, are a superfamily of structurally conserved proteins (fusogens) that mediate three types... →

Abstract: The fact that some amino acid chains fold alone into natively structured and fully functional proteins in solution, has led to the commonly accepted “one sequence-one structure” notion. However,... →

Arie Admon@70 symposia – Celebrating Arie's 35 years of Science "My Life with Mass Spectrometers, Proteomics, and Immunopeptidomics” Thursday, December 22, 2022; 10:00-15:00 Faculty of Biology Auditorium, Technion-Israel Institute of... →

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